- MELODI is a hypothesis generator. It identifies enriched overlapping objects which have been assigned to scientific literature and uses these to derive intermediate mechanisms.
- The underlying annotation objects used for the analysis are semantic predications from the Semantic MEDLINE Datatabase (SemMedDB) and Medical Subject Headings (MeSH).
- Please read the About page to find out more about how to use the application and click on the blue information button at the top of any page for more information.
- Data are stored and investigated using a
graph. To perform a new analysis please Sign in, or to just have a play with some pre-loaded data go to the Results page
Database Details ()
News and Updates
| 20/03/17 | Published in biorxiv - http://biorxiv.org/content/early/2017/03/20/118513 |
| 30/01/17 | List of filtered concepts now available to download. |
| 23/01/17 | Third analysis option included - SemMedDB concepts. |
| 18/01/17 | Can now delete unwanted article sets |
| 13/12/16 | Switched multiple correction method to Benjamini/Hochberg (non-negative) with a 1e-5 cutoff |
| 09/12/16 | Updated concept frequencies per year for MeSH data |
| 21/11/16 | Updated SemMedDB to Version 26 (April 30th 2016). Graph now contains ~700,000 more PubMed articles. |
| 09/11/16 | Added option to share a results page. |
| 26/09/16 | MELODI presented at Big Data in Biology and Health. |
| 06/09/16 | Improved performance by modifying graph installation. |